Publications and talks
Downloadable
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My preprints/reprints at
the Los Alamos Preprint Archive (cond-mat) (q-bio)
Refereed
Journals
2011
M.L.
Ferguson, D. Le Coq, M. Jules, S. Aymerich, O.Radulescu, N. Declerck,
C.A. Royer. Reconciling molecular regulatory mechanisms with noise
patterns of bacterial metabolic promoters in induced and repressed
states, in press Proceedings of the National Academy of Sciences.
V.Noel,
D.Grigoriev, S.Vakulenko, O.Radulescu, Tropical geometries and dynamics
of biochemical networks. Application to hybrid cell cycle models.
SASB 2011, in press Electronic Notes in Theoretical Computer
Science. (preprint).
V.Noel,
S.Vakulenko, O.Radulescu, Algorithm
for
Identification of Piecewise Smooth Hybrid Systems: Application to
Eukaryotic Cell Cycle Regulation.
WABI 2011, in press
Lecture Notes in Computer Science 6833 Springer 2011, ISBN 978-3-642-23037-0. (preprint).
A.Crudu, A.Debussche, A.Muller, O.Radulescu, Convergence of stochastic
gene networks to hybrid piecewise deterministic processes,
in press Annals of Applied Probability.
(preprint).
Ovidiu Radulescu, Anne Siegel, Elisabeth
Pécou, Clément Chatelain, Sandrine Lagarrigue.
Genetically regulated metabolic
networks: Gale-Nikaido modules and differential inequalities, in
Transactions in Computational Systems Biology XIII, LNBI 6575, Springer
2011 (preprint).
2010
Baumuratova
T,
Surdez D, Delyon B, Stoll G, Delattre O, Radulescu O,
Siegel A. Localizing potentially active post-transcriptional
regulations in the Ewing's sarcoma gene regulatory network. BMC Systems Biology (2010) 2;4(1):146.
(link).
Carito Guziolowski, Sylvain Blacho, Tatiana
Baumuratova, Gautier Stoll, Ovidiu
Radulescu, Anne Siegel. Designing
Logical
Rules
to
Model the Response of Biomolecular
Networks
with Complex Interactions: An Application to Cancer Modeling. IEEE/ACM Trans.
Comp. Bio. Bioinformatics, 99 (2010) 1545-5963 (link).
A.N.
Gorban, O.Radulescu, A. Zinovyev, Asymptotology of Chemical Reaction
Networks,
Chemical
Engineering Science, Chem.Eng.Sci. 65 (2010) 2310-2324.
(link).
(preprint).
2009
S.Vakulenko, Manu, J.Reinitz, O.Radulescu, Size Regulation in the
Segmentation of Drosophila: Interacting Interfaces between
Localized Domains of Gene Expression Ensure Robust Spatial Patterning,
Phys.Rev.Lett. (2009) 103, 168102.
(link).
also
selected
by
Virtual Journals, Vir.J.Bio.Phys.Res. (2009) 18,9 (link) (preprint)(supplemental).
A.Crudu,
A.Debussche, O.Radulescu, Hybrid stochastic simplifications
for multiscale gene networks, BMC Systems Biology (2009) 3:89.
(link).
P.
Blavy, F. Gondret, H. Guillou, S. Lagarrigue, P.G.P., Martin, J. van
Milgen, O. Radulescu and Siegel, A.
A minimal model for hepatic fatty acid
balance
during fasting: Application to PPAR alpha-deficient mice, Journal of
Theoretical Biology, 261 (2009), pp. 266-278.
B.Lasne,
O.Radulescu, S.Lerouge, Echelles de temps et
instabilités
dans un système rhéofludifiant de micelles
géantes,
à
paraitre dans Rhéologie, revue du GFR.
Manu, S.Surkova,
AV.Spirov, V.Gursky, H.Janssens, A.Kim, O.Radulescu, CE.Vanario-Alonso,
D.H.Sharp, M.Samsonova, J.Reinitz. Canalization
of gene expression and domain shifts in the Drosophila
blastoderm by dynamical attractors, PLoS
Computational
Biology
2009
(link).
Manu, S.Surkova,
AV.Spirov, V.Gursky, H.Janssens, A.Kim, O.Radulescu, CE.Vanario-Alonso,
D.H.Sharp,
M.Samsonova, J.Reinitz. Canalization of gene expression in the
Drosophila
blastoderm by
gap genes cross
regulation, PLoS Biology 2009 (link).
Carito Guziolowski, Jeremy Gruel, Ovidiu
Radulescu, Anne Siegel, Curating a Large-Scale Regulatory Network by
Evaluating
its Consistency with Expression Datasets, accepted LNBI/LNCS series,
Springer (preprint).
2008
Christophe Lavelle,
Hugues Berry, Guillaume Beslon, Francesco Ginelli, Jean-Louis Giavitto,
Zoi
Kapoula, André Le Bivic, Nadine Peyrieras, Ovidiu Radulescu,
Adrien Six,
Véronique Thomas-Vaslin, Paul
Bourgine,
"From Molecules to Organisms: Towards Multiscale Integrated Models of
Biological Systems", Theoretical Biology Insights 2008, 1:13-22.
O.Radulescu, A.N.Gorban, A.Zinovyev, A.Lilienbaum, "Robust simplifications of multiscale biochemical networks", BMC
Systems Biology, 2008, 2:86. (link) highlighted "most accessed" by BMC in november 2008.
Dynamic and static limitation in
reaction networks, revisited
A.N.Gorban and O. Radulescu, invited
paper Advances in
Chemical Engineering, Vol 34, 103-173,
2008.
(preprint)
Inferring the role of
transcription factors as inducers or repressors in regulatory
networks Ph. Veber, C. Guziolowski,
M. Le Borgne, O.Radulescu, and A.Siegel BMC Bioinformatics
2008, 9:228.
(preprint)
2007
Checking Consistency
Between
Expression Data and Large Scale Regulatory Networks: A Case Study
C.Guziolowski, P.Veber, M. Le Borgne, O.Radulescu, A.Siegel, J.Biol.Phys.Chem.
2007, Volume 7, Number 2, p.p. 37-43. (preprint)
Dynamical robustness of
biological
networks with hierarchical distribution of time scales.
A.Gorban, O. Radulescu IET Systems Biology (2007) 1:
238-246. (preprint)
Optimiser un plan d’expérience à partir de
modèles
qualitatifs.
A. Siegel, C.Vargas, Ph. Veber, O. Radulescu, M. le Borgne Biofutur,
(2007) 27-31
Theoremes limites pour des processus de Markov a sauts.
Synthese des
resultats
et applications en biologie moleculaire
O. Radulescu, A. Muller, A. Crudu, TSI (Technique et Science
Informatiques)
(2007) 26/3-4: 443-469. (preprint)
2006
Topology and static
response of
interaction networks in molecular biology.
O. Radulescu, S. Lagarrigue, A. Siegel, , M. Le Borgne, P.
Veber, Royal
Society Interfaces, 3 (2006) 185-196 (preprint)
Qualitative analysis of
the
relation between DNA microarray data and behavioral models of
regulation
networks.
A. Siegel, O. Radulescu, M. Le Borgne, P. Veber, J. Ouy, S.
Lagarrigue, Biosystems
84 (2006) 153-174. (preprint)
1990-2004
Complex Qualitative Models in Biology: a new approach.
Ph.Veber, M. Le Borgne, A. Siegel, O. Radulescu, Complexus 2
(2004-5)
140-151. (preprint)
Theory of Phasons in
Aperiodic Crystals
T. Janssen, O Radulescu, Ferroelectrics 305 (2004) 179-184, (reprint).
Timescales in shear
banding of
wormlike micelles.
O.Radulescu, P.D.Olmsted, J.P.Decruppe, S.Lerouge, J.F.Berret, G.Porte,
Europhys.
Lett. 62 (2) (2003) 230-236. (preprint)
Dynamics of modulated
and
composite aperiodic crystals: the signature of the inner polarization
in the
neutron coherent inelastic scattering.
O Radulescu, T Janssen, and J Etrillard, Eur.Phys.J. B 29
(2002) 385 (reprint).
Phasons, sliding modes
and
friction.
T. Janssen, O. Radulescu, and A.N. Rubtsov, Eur.Phys.J. B 29
(2002)
85-95 (reprint).
Models of Commensurate
and
Incommensurate Composites
O Radulescu, Ferroelectrics 250 (2001) 43-46, (preprint).
Matched Asymptotic
Solutions
for the Steady Banded Flow of the Johnson-Segalman Model in Various
Geometries
O Radulescu and PD Olmsted, Journal of non-Newtonian Fluid Mechanics
91
(2000) 141-162 (preprint), (reprint).
The Johnson-Segalman
model with
a diffusion term: a mechanism for stress selection
PD Olmsted, O Radulescu, and CYD Lu, Journal of Rheology 44 (2000) 257-275 (preprint), (reprint).
One-dimensional
quasicrystals related
to decagonal Al-Co-Ni
S Ritsch, O Radulescu, C Beeli, K Hiraga, R Luck, and DH Warrington, Philosophical
Magazine
Letters
80 (2000) 107-118
Shear-banding in
reaction-diffusion models
O Radulescu and PD Olmsted, Rheologica Acta 38 (1999) 606-613, (reprint).
Sliding mode and
analyticity
breaking in the double-chain model of incommensurate composites
O Radulescu and T Janssen, PHYSICAL REVIEW B-CONDENSED MATTER 60
(1999)
12737-
12745,
(preprint).
Pinning and phonon
localization
in Frenkel-Kontorova models on quasiperiodic substrates
TS vanErp, A Fasolino, O Radulescu, and T Janssen, PHYSICAL REVIEW
B-CONDENSED MATTER 60 (1999) 6522- 6528, (preprint).
Arithmetic properties
of
spectra produced by Farey hierarchies of approximants
O Radulescu and T Janssen, JOURNAL OF MATHEMATICAL PHYSICS 40
(1999)
1317- 1333., (reprint).
Domain wall motion in
aperiodic
crystal systems and magnetoelectrics
T Janssen and O Radulescu, Zeitschrift fur Physik B 104 (1997)
657-660.
Dynamics of lattice
vibrations
for 1-D commensurate and incommensurate composites with harmonic
interaction
O Radulescu and T Janssen, Journal of Physics A 30 (1997)
4199-4214, (reprint).
Coincidence
quasilattices and
coincidence modules for icosahedral quasicrystals
DH Warrington, O Radulescu and R Luck, Acta Crystallographica A53
(1997)
314-328.
Twins of quasicrystals
and of
rational approximants
O Radulescu and DH Warrington, Materials Science Forum 207-209
(1996)
329-332.
An elementary approach
to the
crystallography of twins in icosahedral quasicrystals
O Radulescu, Journal de Physique I France 5 (1995) 719-728.
Arithmetic properties of
quasicrystals, coincidence modules and coincidence quasilattices
O Radulescu and DH Warrington Acta Crystallographica A51
(1995) 134-156.
A classification of the
periodic
directions in the rational approximants of icosahedral quasicrystals
O Radulescu, Journal de Physique I France 3 (1993) 2099-2113.
A visibility threshold
for rational
approximants
O Radulescu and M Kléman, Journal of Non-crystalline Solids 153-154
(1993)
227-231.
Périodicité et
quasi-périodicité dans les
structures à ordre local
icosahédrique
O Radulescu and M Kléman, Comptes-rendus de
l'Académie des Sciences t.315
II (1992) 1629.
On the bond
orientational order
in icosahedral phases
O Radulescu and R Manaila, Physica Status Solidi (b) 161
(1990) 65.
On the transition-metal
quasisublattice in icosahedral Al-Cr-Fe phases
R Manaila, V Florescu, A Jianu and O Radulescu, Philosophical
Magazine B
60 (1989) 589-599.
Conference
Proceedings
Ovidiu Radulescu, Alexander
Gorban, and Andrei Zinovyev. Pruning, pooling and limiting steps in
metabolic
networks. Proceedings of Evry school 2010 "Modelling Complex Biological Systems in the Context
of Genomics". (preprint).
Sylvain Blachon,
Gautier Stoll,
Carito Guziolowski,
Andrei Zinovyev,
Emmanuel Barillot,
Anne Siegel,
Ovidiu Radulescu:
Method for Relating Inter-patient Gene
Copy Numbers Variations with Gene Expression via Gene Influence
Networks.
AIAI
Workshops
2009: 72-87
Static and Dynamic
properties of
commensurate ans incommensurate composites
O Radulescu and T Janssen, in Proceedings of the International
Conference on
Aperiodic Crystals Aperiodic '97, M de Boissieu, JL Verger-Gaugry
and R Currat edts., World
Scientific (1998).
Phason flips and
reconstruction
of grain boundaries in quasicrystals
O Radulescu, DH Warrington and R Luck, in Proceedings of the
International
Conference on Aperiodic Crystals Aperiodic '97, M de Boissieu,
JL
Verger-Gaugry and R Currat edts., World Scientific (1998).
Talks 2005-2007
Aspects stochastiques de la dynamique de reseaux en biologie
moleculaire
(in French) (slides)
Raisonnements qualitatifs sur reseaux : applications en genomique
fonctionnelle, seminaire Institut Curie 2005, (in French) (slides)
Concentration and
spectral robustness of biological networks, ECCS'05 (in English) (slides)
New qualitative
approaches in molecular biology, Bangalore
meeting 2006 (in English) (slides)
Hierarchies and modules
in complex biological systems, ECCS conference september 2006 (in
English) (slides)
Modèles mathématiques de la complexité en
biologie moléculaire et en
mécanique des fluides
Habilitation à diriger des recherches soutenue le 11/12/2006
(document de synthèse)(slides)(live)
Improving model
consistency by qualitative equations, INRIA-NIH meeting Bethesda April
2007 (in English) (slides)
Interfaces and shear
banding, Euromech meeting on "Shear Banding" London September 2007 (in English) (slides)
Hierarchical models in
systems biology, CEA-EDF-INRA
School "Model
Reduction" Rocquencourt October 2007 (in English) (slides)
Mathématiques des cellules, conférence grand public
dans le
"Festival des sciences" de Rennes Metropole, Octobre 2007 (in french)
(slides)
Manuscripts
Diffusion neutral and
diffusion dependent patterning
O. Radulescu, S. Vakulenko, (preprint)
A model for regulated
fatty acid metabolism in liver; equilibria and their changes
O. Radulescu, A. Siegel, E. Pecou, S. Lagarrigue (preprint)
Hierarchies and modules
in complex biological systems
O. Radulescu, A. Gorban, S. Vakulenko, A. Zinovyev presented at
ECCS'06 (preprint)
Model reduction and
model comparison for NFkB signaling.
O. Radulescu, A. Zinovyev, A.Lilienbaum FOSBE'07 (preprint)
Back to the O.Radulescu
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Ovidiu.Radulescu@univ-rennes1.fr
Last
modified 20 january 2007